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first_img With Pinnacle´s HD mini Stick viewers can enjoy clear, sharp pictures on their PC or Mac. The mini-Stick supports digital over-the-air TV (ATSC) and unencrypted digital cable TV (ClearQAM) for SDTV and HDTV with resolutions of up to 1080i.With Pinnacle´s TV Center Pro 5 software, viewer´s can record and watch high-quality SD and HD TV shows on their personal computer. Viewers can also record TV shows in MPEG-1, MPEG-2 or DivX formats and save the programs on a hard drive or directly to a DVD. Pinnacle also includes a trial version for MPEG-4 support that allows users to output to a Sony PSP or an Apple iPod. In the software package you will also find VideoSpin which allows users to quickly trim the length of their recordings.The HD mini Stick comes with a mini remote control, high-gain telescopic antenna, video recording and editing software and a travel bag. Pinnacle PCTV HD mini Stick and Pinnacle TV for Mac HD mini Stick will be available in stores and online by September 21. The suggested retail price for the PCTV HD mini Stick is $119.99 and $129.99 for the Pinnacle TV for Mac HD mini Stick, which will also be available in selected Apple Stores.Via: Pinnacle Image courtesy of Pinnacle Explore further Citation: Pinnacle Unveils Compact USB Digital HDTV Tuner (2008, September 8) retrieved 18 August 2019 from https://phys.org/news/2008-09-pinnacle-unveils-compact-usb-digital.html 2010 sees Apple at pinnacle of tech industry Just in time for the Fall Season TV line up, Pinnacle has introduce their new ultra-compact HDTV tuner with some features found in DVR’s. With Pinnacle´s HDTV Stick you can also pause live TV and record shows to a hard drive or DVD. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

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first_img Resistant gut bacteria will not go away by themselves More information: High Frequency of Horizontal Gene Transfer in the Oceans, Lauren D. McDaniel et al. Science 1 October 2010: Vol. 330. no. 6000, p. 5. DOI:10.1126/science.1192243 (PhysOrg.com) — A new study suggests that genes are transferred from one micro-organism to another up to a hundred million times more frequently than previously thought. Explore further A. TEMs of GTA particles of Roseovarius nubinhibens ISM (bar = 20 nm). B. TEMs ofGTAs produced by Reugeria mobilis 45A6 (bar = 50 nm). Image credit: Science , DOI:10.1126/science.1192243 Virus-like particles called gene transfer agents (GTAs) are produced by alpha-proteobacteria and pass from one microbe to another, taking random pieces of genetic material up to 1,000 bases long with them. The high frequency with which this has been found to occur may provide a mechanism by which bacteria in the oceans acquire novel traits, and may play an important role in evolutionary processes.One of the researchers, marine microbiologist John Paul, of the University of South Florida College of Marine Science in St Petersburg, said scientists had known “there’s a lot of gene shuffling going on in bacteria,” but until now no one had found a plausible mechanism for this horizontal gene transfer (as opposed to transfer of genes down the generations).The existence of GTAs has been known since their discovery in 1974, but until now they were considered merely curiosities or laboratory anomalies. In the laboratory bacteria only produce GTAs in their “stationary phase”, which occurs when they are under stress through crowding, waste buildup and so on. The extent to which they play a part in nature outside of the laboratory was previously unkown, but they have been found in most members of the alpha-proteobacteria. The team led by Paul first genetically engineered GTAs in two species of alpha-proteobacteria to contain a set of genes that conferred antibiotic resistance. They stressed the bacteria to initiate the stationary phase, and then filtered out and purified the GTAs.They then sealed the GTAs in bags of seawater drawn from a variety of coastal environments in Florida and the Gulf of Mexico. The water samples were teeming with alpha-proteobacteria and other microbes. The bags were then floated in the ocean to simulate natural conditions. After incubation in antibiotics overnight, the various kinds of bacteria surviving in the samples were examined and genetically sequenced. The researchers found up to 47% percent of the naturally occurring bacteria had incorporated the GTAs and their genetic contents into their own genomes.Lauren McDaniel, one of the co-authors of the paper said they were “absolutely amazed to see exact matches for the genes we put into the donor strain in different genera…” There are other means of horizontal gene transfer, such as cell to cell contact, by plasmids (mobile genetic elements) or by bacterial viruses, but these were unlikely to produce the results found.The paper, published in the journal Science may help explain how bacteria can rapidly adapt to change, and quickly become resistant to antibiotics. Genes spread horizontally to other bacteria can lead to an increase in the frequency of those genes if they are beneficial and lead to better chances of survival. © 2010 PhysOrg.com Citation: Horizontal gene transfer in microbes much more frequent than previoulsy thought (2010, October 4) retrieved 18 August 2019 from https://phys.org/news/2010-10-horizontal-gene-microbes-frequent-previoulsy.html This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

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first_img © 2010 PhysOrg.com Called the Vax ev, the cleaner is designed to be assembled at home by the customer using the cardboard from the box in which it is shipped. The cardboard is pretreated with fire retardant, and because it is the corrugated variety, it is assumed it will be able to withstand the rigors of home vacuuming, though, it isn’t clear just yet how long such a vacuum cleaner would last. In its favor, the entire housing can be easily and cheaply replaced, and customers with some foresight might in fact purchase some extra corrugated cardboard from their local packaging store, along with their new vacuum and then use the original panels as a pattern for fashioning their own replacement panels thus avoiding having to go to the manufacture when their new vac runs afoul of some heavy furniture or perhaps a bit of a liquid spill.Vax, the U.K.s leading floor-care brand says that the new model will be a limited edition, as it’s uncertain just how many customers would actually buy such an appliance. Explore further This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. More information: via Press release Perfect packaging The housings for traditional vacuum cleaners are generally made of injection molded plastics of the type that take a very long time to decay in a landfill and require large centralized plants to make, which means large transportation costs and more air pollution. With rapid process manufactured plastics, such as those used for the inside parts of the Vax ev, parts can be made almost anywhere, making it easier to set up small plants that are closer to the customer.In an interesting side-feature, future owners of the Vax should be able to very easily customize their vacuums with felt tip pens, creating designs that might make the vacuum look a little less like a cardboard box with wheels, and more like a piece of art, or even perhaps, more like the plastic covered models that home vacuumer’s are used to seeing. Citation: College student invents cardboard vacuum cleaner (2011, July 7) retrieved 18 August 2019 from https://phys.org/news/2011-07-college-student-cardboard-vacuum-cleaner.html (PhysOrg.com) — In another attempt to reduce the amount of plastic refuse that winds up in landfills, Jake Tyler, an industrial design student at Loughborough University has devised a means to construct a working vacuum cleaner out of corrugated cardboard. The vacuum, developed as part of his final year degree project in conjunction with a design team from Vax, where Tyler is now employed, has its housing made of cardboard, while the inside motor works employs recyclable pure nylon plastic using rapid process manufacturing, rather than injection molding.last_img read more

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first_img Discovered: How to unlock inaccessible genes This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Explore further As Keung and Khalil note, research into chromatin organization is rapidly advancing and because of that advances have been made in better understanding many disease processes. Most of this research, they note, has taken place at the cellular level. In this new effort the researchers took what they describe as an “algorithmic” approach to the study and structure of chromatin biology. Their approach is based on looking at the way individual chromatin regulators operate to produce the different gene expressions that occur. In so doing, they came up with a model that Keung and Khalil describe as both elegant and unifying.The model is based on the development of a framework to quantitatively describe the behavior of individual chromatin regulators (CRs) taking into consideration how they modulate gene expression, how permanent the changes are and how they relate to one another. The framework is then used to compare four distinct repressive CRs using longitudinal measurements they took of single cells via time-lapse microscopy. The end result is a three-state model that allows for capturing the dynamics of nongenetic influences on gene expression.Because the model they built is so simple, it is not well suited for the study of higher level biochemical problems, Keung and Khalil point out, but suggest that connecting the model with data obtained via prior studies should prove interesting. They also note that building such a model is important because it helps to bring logic to the problem of conceptualizing the complexity of chromatin biology. More information: Dynamics of epigenetic regulation at the single-cell level, Science  12 Feb 2016: ol. 351, Issue 6274, pp. 720-724, DOI: 10.1126/science.aab2956, http://science.sciencemag.org/content/351/6274/720AbstractChromatin regulators play a major role in establishing and maintaining gene expression states. Yet how they control gene expression in single cells, quantitatively and over time, remains unclear. We used time-lapse microscopy to analyze the dynamic effects of four silencers associated with diverse modifications: DNA methylation, histone deacetylation, and histone methylation. For all regulators, silencing and reactivation occurred in all-or-none events, enabling the regulators to modulate the fraction of cells silenced rather than the amount of gene expression. These dynamics could be described by a three-state model involving stochastic transitions between active, reversibly silent, and irreversibly silent states. Through their individual transition rates, these regulators operate over different time scales and generate distinct types of epigenetic memory. Our results provide a framework for understanding and engineering mammalian chromatin regulation and epigenetic memory. Citation: Researchers find that chromatin’s complexity can be reduced into a unifying model of gene regulation (2016, February 12) retrieved 18 August 2019 from https://phys.org/news/2016-02-chromatin-complexity-gene.htmlcenter_img (Phys.org)—A team of researchers made up of members from the California Institute of Technology, Tottori University and the Howard Hughes Medical Institute has conducted a study that has led to finding that that the material of which chromosomes are composed (chromatin) can be reduced to a unifying model of gene regulation. In their paper published in the journal Science, the team describes their approach and why they believe it may lead to a better understanding of the way the expression of the genome is controlled. Albert Keung and Ahmad Khalil with North Carolina State University and Boston University respectively, offer a Perspective piece on the work done by the team in the same journal edition and offer some insight into the direction such work appears to be heading in the near future. The structures of A-, B-, and Z-DNA. Credit: Richard Wheeler/ Wikipedia Journal information: Science © 2016 Phys.orglast_img read more

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first_imgCredit: © Jessica Fujii Explore further Citation: Genetic study of sea otters suggests very long history of tool use (2017, March 22) retrieved 18 August 2019 from https://phys.org/news/2017-03-genetic-sea-otters-history-tool.html © 2017 Phys.org Endangered sea otters fly into France (Phys.org)—A team of researchers affiliated with several institutions in the U.S. has found via genetic analysis that tool use by sea otters appears to go back hundreds of thousands or even millions of years. In their paper published in the journal Biology Letters, the team describes how they looked for genetic differences between groups of otters and compared their findings with tool use in bottlenose dolphins to learn more about the history of tool use in marine animals.center_img Journal information: Biology Letters Tool use by land animals, particularly primates and birds, has been extensively studied, the researchers note, but little attention has been paid to tool use by marine animals. In this new effort, they looked at sea otters, which use rocks to break open shelled prey. They also studied bottlenose dolphins, which use sponges to protect their noses as they search among sharp rocks for food.To measure how long otters have been using tools, the team conducted a genetic analysis on several specimens from multiple sites across the Pacific Ocean to determine how closely related they were to one another. They worked under the assumption that if groups of otters that used tools were more closely related to other otter tool users than to non-users, then it was likely tool use was a relatively recent development because it had not permeated to all otters everywhere. But, they found, this was not the case at all—otters that used tools were found to be no more related to other tool users than to groups that did not use tools. When the team conducted the same type of analyses on dolphins, they found the opposite to be true. Groups that used sponges were more closely related to one another than to other groups of the same species that did not use sponges. This, the researchers contend, suggests that sea otters have been using tools for so many generations that it is now part of their basic makeup, which would take hundreds of thousands or millions of years to come about—possibly going back to the time when our human ancestors first began using tools. The bottle nosed dolphins, on the other hand, appear to be part of a group of tool users going back just a few hundred years. More information: Mitogenomes and relatedness do not predict frequency of tool-use by sea otters, Biology Letters, rsbl.royalsocietypublishing.or … .1098/rsbl.2016.0880AbstractMany ecological aspects of tool-use in sea otters are similar to those in Indo-Pacific bottlenose dolphins. Within an area, most tool-using dolphins share a single mitochondrial haplotype and are more related to each other than to the population as a whole. We asked whether sea otters in California showed similar genetic patterns by sequencing mitogenomes of 43 otters and genotyping 154 otters at 38 microsatellite loci. There were six variable sites in the mitogenome that yielded three haplotypes, one found in only a single individual. The other two haplotypes contained similar percentages (33 and 36%) of frequent tool-users and a variety of diet types. Microsatellite analyses showed that snail specialists, the diet specialist group that most frequently used tools, were no more related to each other than to the population as a whole. The lack of genetic association among tool-using sea otters compared with dolphins may result from the length of time each species has been using tools. Tool-use in dolphins appears to be a relatively recent innovation (less than 200 years) but sea otters have probably been using tools for many thousands or even millions of years. This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

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first_img‘The Eternal Radha’ is Suhas’s concept of a mysterious heroine, an image of a perfect woman who is intriguingly garbed as a muse in his works. He recreates the beauty of  nature and stirs the romantic version of the classic in two dimensions in his paintings. He also focuses his portrayal of the female subjects in his works with a special, pristine agelessness. Suhas puts a vital rhythm into the visual sensation, the dynamic equilibrium of forms, the virtues of distinct serenity, and  an unruffled essence of form in his recent works. All the creations are a visual extravaganza with the muse Radha displayed in varying forms. Suhas’ works of art include a skilful execution, varied techniques, adept brush strokes, and the subtle and interesting use of colours. Their fluid strokes immediately elicit a dialogue with the viewer because of their appeal on the visual statement and the underlying mystique of tradition and symbolism embodied in the treatment of their subjects.When: 6 January till 31 January, 11.00 amWhere: Dhoomimal City Gallerylast_img read more

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first_imgKolkata: Dr Subhash Mukherjee, the creator of India’s first test-tube baby, who committed suicide after the Left Front government had allegedly neglected his research and was harassed by the then strong gynecologists’ lobby, has been paid due respect posthumously by the Mamata Banerjee government for his enormous contribution to modern reproductive system as it named prestigious chairs at two state-run medical colleges in the city after him.Dr Mukherjee, who pioneered in-vitro fertilization (IVF) in India, created the Country’s first test tube baby, Kanupriya Agarwal, alias Durga, in October 1978 inside his house in Kolkata with the help of some general apparatus and a refrigerator. Also Read – Heavy rain hits traffic, flightsHe eventually committed suicide in 1981 after failing to get recognition. He could not handle constant criticism and the outright harassment he was subjected to.After coming to power, the Mamata Banerjee government has showed respect to Dr Mukherjee by naming chairs after him at the Physiology department of the NRS Medical College and Hospital and also in the School of Tropical Medicine. The Endocrinology building at the NRS Medical College and Hospital Also Read – Speeding Jaguar crashes into Merc, 2 B’deshi bystanders killedhas been named after him for his contribution towards the modern reproductive technology.Since his feat did not receive due acknowledgement from the scientific community, he might have taken a drastic step. He had to face humiliations when he was transferred to Bankura Sammilani Medical College and Hospital from the Physiology department of the NRS Medical College and Hospital. He was again transferred to RG Kar Medical College and Hospital before being shunted to the Regional Institute of Opthalmology in Kolkata in June 1981 where there was no physiology department. He had committed suicide within a few weeks after he was shunted. The West Bengal government set up an enquiry committee to investigate the matter in 1978. The committee concluded that his claim was false. It was said that the committee that condemned Dr Mukherjee’s procedure reportedly comprised a gynaecologist, a psychologist, a physicist and a neurologist—none of whom had any knowledge of modern reproductive technology. The Left front government had argued that Dr Mukherjee lacked sufficient documentation. In the year 2002, the Indian Council of Medical Research (ICMR) recognised his work for the first time.He went to Edinburgh University in the UK for a PhD in reproductive endocrinology after studying at the National Medical College and Hospital. After his return, he started his research in ovulation and spermatogenesis. Within a year, he announced the birth of the world’s second test-tube baby with a team comprising Sunit Mukherji, a cryobiologist, and Saroj Kanti Bhattacharya, a gynaecologist. Dr Mukherjee was born at Hazaribagh in Jharkhand. It came only 67 days after the British biologist Robert Edwards had announced the birth of the first test-tube baby in England. But unlike Edwards, Dr Mukherjee’s method of cryopreservation to preserve the human embryo is currently the preferred technique of medically assisted reproduction worldwide.last_img read more

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first_imgPope Francis said on Sunday the plight of asylum seekers hoping for a new life in Europe was enough to make him cry, condemning those who treat them “like merchandise”.Speaking during his first pastoral visit to northern Italy, the pontiff slammed hostility towards migrants arriving by boat from Libya, with European countries bickering over who should be forced to provide shelter to the needy.“It brings tears to one’s eyes to see the spectacle of these days, in which human beings have been treated like merchandise,” he told the crowds. Also Read – Pro-Govt supporters rally as Hong Kong’s divisions deepenHe was speaking as Italian Prime Minister Matteo Renzi met his French counterpart Francois Hollande in Milan to discuss the immigration crisis which has seen hundreds of migrants blocked on the border between the two countries.The head of the world’s 1.2 billion Catholics was in the industrial city in the northwest of the country for a two-day visit which saw him spend time with the poor, sick and marginalised, including prisoners and migrants.Francis, whose father grew up in the city, was in Turin to pray before the mysterious shroud, believed by Christians to be the burial cloth of Jesus but held by sceptics to be a medieval fake.Sitting before it in silence in the city’s cathedral, Francis remained with his head bowed in prayer before rising to contemplate up close the linen cloth which bears the faint image of a man who appears to have died by crucifixion.last_img read more

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first_imgKolkata: Speculations are on over five Congress MLAs joining Trinamool. Though Trinamool leaders are tightlipped over the issue, sources said that they have met party secretary general Partha Chatterjee and submitted a letter expressing their willingness to join the party.These MLAs are Moinul Haque, Abu Taher Khan and Akhrujjaman from Murshidabad and Samar Mukhopadhyay and Sabina Yasmin from Malda. Apurba Sarkar, an MLA from Murshidabad, has already joined Trinamool Congress.It may be mentioned that 11 Congress MLAs have already joined Trinamool and with the joining of these five, the total number of Congress MLAs joining the ruling party will be 16.Congress got 44 seats when Trinamool came back for the second time after the 2016 Assembly election. Madhusudan Ghosh, who was elected from Noapara, died and so a by-election was held, which Trinamool won. Manas Bhuniya joined Trinamool and is now a Rajya Sabha member.With the joining of three MLAs, Murshidabad Congress will be the worst hit. Trinamool Congress supremo Mamata Banerjee had appointed Suvendu Adhikari to look after the district, which was said to be a Congress stronghold under Adhir Chowdhury.Under Adhikari’s leadership, Trinamool won the Panchayat election and he persuaded 11 leaders to join Trinamool. Murshidabad is a traditional Congress stronghold, where Atish Chandra Sinha was the leader of Opposition. Chowdhury had trouble with Sinha, who later became insignificant in Murshidabad politics.Though Trinamool had bagged 211 seats in 2016, it does not have any representation in Malda, after two of its ministers, Krishnendu Narayan Chowdhury and Sabitri Mitra, lost. Malda is a Congress stronghold since the time of ABA Ghani Khan Chowdhury. With the joining of two MLAs, Congress will lose much of its steam in the district.Speculations are on that Khan Chowdhury’s brother AHA Khan Chowdhury and his niece Mousum Noor are likely to join Trinamool as well.last_img read more

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first_imgKolkata: State Power minister Sobhandeb Chattopadhyay on Saturday inaugurated a “Wild Tiger Photography Competition cum Exhibition” at Gaganendra Pradarshanshala at the premises of Nandan. The three-day event was organised by an NGO that works for wildlife conservation to mark the occasion of World Tiger Day (July 29).”The census often does not correctly reflect the count of tigers. The location of our forests is such, that often tigers travel to the neighbouring states and country like Bangladesh across the border. These NGO’s and wildlife enthusiasts work at the ground level for tiger conservation and educate the villagers living near the forests, stating not to kill the wild animals. They have been doing good work in collaboration with the state Forest department,” Chattopadhyay said. Also Read – Rain batters Kolkata, cripples normal lifeReferring to the incidents of tiger straying, the minister said loss in forest cover for urbanization is leading animals like tiger to sneak into localities.He also stressed on the need to spread awareness among the tribals in the state to not indulge in the killing of the animals for sport.”The government in association with the NGOs are working towards awareness and at the same time, taking steps for the upliftment of the economic condition of the tribals,” he added. Photographs of 80 wildlife photographers were displayed at the exhibition.last_img read more